Fig. 2
From: A novel fibrinogen mutation: FGA g. 3057 C > T (p. Arg104 > Cys) impairs fibrinogen secretion
Fibrin factor XIIIa crosslinking. a control fibrinogen, (b) fibrinogen from father. Fibrin was cross-linked by the endogenous FXIII co-precipitated with fibrinogen. Polymerisation and crosslinking was initiated by addition of thrombin/CaCl2 and samples removed at different incubation times and run on 8%SDS/PAGE gels under reducing conditions.α-p: α-polymers